Blood under pressure: how climate change threatens blood safety and supply chains

Climate change substantially threatens public health, including the blood supply chain, which is crucial for medical treatments such as surgeries, trauma care, and chronic disease management. Extreme weather events, vector-borne disease shifts, and temperature fluctuations can disrupt blood collection, testing, transport, and storage, threatening both the safety and sufficiency of blood products. Although studies have highlighted some connections between climate change, transfusion-transmissible infections, and blood safety, there remains a lack of comprehensive understanding of the climate effects on each supply chain stage. In this Personal View, we address the potential climate-driven challenges across the blood supply chain, from donor health to blood component stability, emphasising the importance of proactive measures. To protect the availability and safety of blood supplies in an evolving climate, further research and adaptive strategies are needed to build a resilient blood supply system that can withstand emerging climate-related disruptions.