Climate change impacts the symptomology and healthcare of multiple sclerosis patients through fatigue and heat sensitivity - A systematic review

Background

Climate change, in terms of global warming and heat waves, might negatively impact people with neurological diseases. Patients with Multiple Sclerosis (MS), which is characterized by heat sensitivity, may therefore have an increased vulnerability. Subsequently, we aimed to specifically investigate the state of knowledge on climate change and MS.

Methods

We conducted a literature search in the Pub Med database during 2022–2024 using the search terms “multiple sclerosis” AND “climate “, “climate change”, “global warming”, “heat waves”, and “seasonal variations”. A total of 773 scientifical papers were retrieved and scrutinized according to the inclusion/exclusion criteria. Finally, 24 publications were manually selected based on their relevance to the intended topic, covering climate change related heat sensitivity in MS patients, associated healthcare burden, and treatment strategies.

Results

Only few publications focused on climate change and its effect on MS. The search yielded 24 articles on effects of climate/environmental heat and seasonal variations on MS. There was both evidence of worsened clinical symptoms as well as negative studies. However, the majority of selected papers, 16/24 (67 %) revealed an impact on MS symptoms/hospitalization from environmental heat.

Conclusions

So far there has been limited interest in the vulnerability of MS patients to climate change. The future perspective of increased temperature and heat waves should be highlighted so that authorities prepare health systems to apply to this new, but logical and intuitive, scientific knowledge. As heat sensitivity also seems to affect neurological disorders beyond MS, further research is needed to develop general care strategies in the future.