Vaccination to mitigate climate-driven disruptions to malaria control in Madagascar

The increasing prevalence of extreme weather events creates severe disruptions to public health, as well as to the environment. In the wake of two successive cyclones hitting Madagascar in 2022 and 2023, Rice et al. examined the effect of these extreme weather events in a high-malaria region. In the aftermath, infection rates by the mosquito-vectored parasite increased to 10% for school-aged children within 3 months as mosquito and malaria control activities were interrupted. Modeling showed that the recently available vaccines supply prolonged protection (up to 10 months) against repeat malaria infections and offer a sustainable instrument for health resilience in the wake of climate change. —Caroline Ash